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EFEK LAKSATIF KOPI ROBUSTA (Coffea canephora Pierre ex A. Froehner) DAN MINYAK ZAITUN (Olea europaea L.) PADA MENCIT (Mus musculus Linnaeus, 1758)
Constipation is a difficult condition to urinate that is generally overcome with laxatives that are widely available on the market such as dulcolax. Robusta coffee and olive oil have a substance that can stimulate intestinal movement so it can be used as an alternative remedy for constipation. The research was conducted to determine the laxative effect on the intake of robusta coffee powder and olive oil. The study used 28 tests divided into 7 groups: negative control group (warm water), positive control (dulcolax), administration of 0,025 g of robusta coffee powder, administration of 0.08 ml of olive oil, and 3 trial groups of dose variation of 0.10 g; 0.05 g; and 0.025 g mixed with 0,08 ml of oil. The laxative effect is tested using the intestinal transit method. Data analysis was done using one way ANOVA and further DMRT testing. The results of the study showed that the group administering 0.10 g of robusta coffee powder mixed with 0.08 ml of olive oil had the highest percentage of intestinal ratio passed by the marker. Administration of 0.025 g of Robusta Coffee powder, and the dose variation of 0.10g; 0.05 g; and 0.025 g blended with olive Oil 0.08 ml differs significantly with positive control (dulcolax). Based on the study results, it was concluded that the administration of variation in the dose of robust coffee powders and olive oils on the mice can significantly affect the result of the ratio of norite spacing with the length of the intestine mice and the consumption of 0,10 g robusta coffe powder mixted with 0.08 mL of oil provides the greatest laxative effect on mice.
FAKULTAS SAINS DAN TEKNOLOGI, UIN SUNAN KALIJAGA YOGYAKARTA
EFEK LAKSATIF KOPI ROBUSTA (Coffea canephora Pierre ex A. Froehner) DAN MINYAK ZAITUN (Olea europaea L.) PADA MENCIT (Mus musculus Linnaeus, 1758) (Text)
EFEK LAKSATIF KOPI ROBUSTA (Coffea canephora Pierre ex A. Froehner) DAN MINYAK ZAITUN (Olea europaea L.) PADA MENCIT (Mus musculus Linnaeus, 1758) (Other)
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