%A NIM.: 22106040037 Fasya Fatima Anggraeni
%O Agessty Ika Nurlita, M.Si.
%T UJI ANTIBAKTERI DAUN KEPEL (Stelechocarpus burahol) DENGAN PELARUT ETANOL DAN ETIL ASETAT PADA FORMULASI PASTA GIGI
%X Dental caries is caused by Streptococcus mutans. Fluoride, a key ingredient in conventional toothpaste, plays a major role in enamel remineralization, but it has limited antibacterial effects and carries a risk of side effects, so herbal alternatives are needed. This study determined the most effective concentration of kepel leaf (Stelechocarpus burahol) extract, using ethanol 70% and ethyl acetate as solvents, as an antibacterial agent against S. mutans, and formulated and evaluated a toothpaste containing the extract. Maceration extraction yielded 13.26% (ethanol) and 8.69% (ethyl acetate). Disc diffusion testing at concentrations of 5%, 10%, and 15% showed significantly different inhibition zones among concentrations (Kruskal-Wallis, p<0.01), with no significant effect of solvent type (Mann-Whitney); 10% and 15% were selected as the best concentrations. Toothpaste formulated with both concentrations met SNI standards (organoleptic properties, homogeneity, pH, spreadability), except for the foaming capacity of the 10% ethanol formula. Inhibition zones of the toothpaste at 10% and 15% were significantly larger than the negative control but smaller than chlorhexidine. Kepel leaf extract shows potential as a natural antibacterial agent for toothpaste, although its activity remains weaker than synthetic active ingredients.
%K Antibakteri, Daun Kepel, Pasta Gigi, Stelechocarpus Burahol, Streptococcus Mutans
%D 2026
%I UIN SUNAN KALIJAGA YOGYAKARTA
%L digilib79626