eprintid: 79626 rev_number: 10 eprint_status: archive userid: 12460 dir: disk0/00/07/96/26 datestamp: 2026-11-02 03:28:58 lastmod: 2026-11-02 03:28:58 status_changed: 2026-11-02 03:28:58 type: thesis metadata_visibility: show contact_email: muh.khabib@uin-suka.ac.id creators_name: Fasya Fatima Anggraeni, NIM.: 22106040037 title: UJI ANTIBAKTERI DAUN KEPEL (Stelechocarpus burahol) DENGAN PELARUT ETANOL DAN ETIL ASETAT PADA FORMULASI PASTA GIGI ispublished: pub subjects: 510 divisions: jur_bio full_text_status: restricted keywords: Antibakteri, Daun Kepel, Pasta Gigi, Stelechocarpus Burahol, Streptococcus Mutans note: Agessty Ika Nurlita, M.Si. abstract: Dental caries is caused by Streptococcus mutans. Fluoride, a key ingredient in conventional toothpaste, plays a major role in enamel remineralization, but it has limited antibacterial effects and carries a risk of side effects, so herbal alternatives are needed. This study determined the most effective concentration of kepel leaf (Stelechocarpus burahol) extract, using ethanol 70% and ethyl acetate as solvents, as an antibacterial agent against S. mutans, and formulated and evaluated a toothpaste containing the extract. Maceration extraction yielded 13.26% (ethanol) and 8.69% (ethyl acetate). Disc diffusion testing at concentrations of 5%, 10%, and 15% showed significantly different inhibition zones among concentrations (Kruskal-Wallis, p<0.01), with no significant effect of solvent type (Mann-Whitney); 10% and 15% were selected as the best concentrations. Toothpaste formulated with both concentrations met SNI standards (organoleptic properties, homogeneity, pH, spreadability), except for the foaming capacity of the 10% ethanol formula. Inhibition zones of the toothpaste at 10% and 15% were significantly larger than the negative control but smaller than chlorhexidine. Kepel leaf extract shows potential as a natural antibacterial agent for toothpaste, although its activity remains weaker than synthetic active ingredients. date: 2026-08-27 date_type: published pages: 118 institution: UIN SUNAN KALIJAGA YOGYAKARTA department: FAKULTAS SAINS DAN TEKNOLOGI thesis_type: skripsi thesis_name: other citation: Fasya Fatima Anggraeni, NIM.: 22106040037 (2026) UJI ANTIBAKTERI DAUN KEPEL (Stelechocarpus burahol) DENGAN PELARUT ETANOL DAN ETIL ASETAT PADA FORMULASI PASTA GIGI. Skripsi thesis, UIN SUNAN KALIJAGA YOGYAKARTA. document_url: https://digilib.uin-suka.ac.id/id/eprint/79626/1/22106040037_BAB-I_IV-atau-V_DAFTAR-PUSTAKA.pdf document_url: https://digilib.uin-suka.ac.id/id/eprint/79626/2/22106040037_BAB-II_sampai_SEBELUM-BAB-TERAKHIR.pdf